Description
Qualitative Detection Of Antibodies Against Canine Distemper Virus
Test applicable to: Dog
Sample: Whole Blood, Plasma or Serum
FASTest CDV Ab is a rapid immunochromatographic ‘lateral flow’ test for the semi-quantitative assay of Canine Distemper Virus IgG-antibodies in canine serum or plasma.
FASTest CDV Ab. allows the veterinarian to make a fast decision concerning the best time to vaccinate, especially in puppies where the presence of maternal antibody can neutralise the vaccine.
Maternal Antibodies
The antibodies are basic modules of the humoral immune response which are passed passively via the colostrum as so-called maternal antibodies (mAb). These are passed onto new-borns or induced actively by natural field infection or vaccination.
These antibodies can vary in quantity in each individual animal depending on multiple factors.
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Reasons for using FASTest CDV Ab
The antibody titre can persist over an extended period of time, sometimes lifelong, inefficient protection concentration (= reliable immunity by protective antibodies) or can fall below the efficient protection concentration (non-reliable immunity) in the course of time.
Therefore knowing the level of individual antibody titre, the veterinarian is able to decide quickly and reliably the necessity of vaccination or no vaccination.
Individual Vaccination Point Of The Breeding Bitch
In problematic breedings, the determination of the antibody status of the female during pregnancy enables the veterinarian to decide whether a booster vaccination before birth is necessary. This is needed to find the optimal primary vaccination time of the puppies, which is a critical stage (so-called immunity gap), especially in the first 12 weeks.
During the first 12 weeks, the concentration of mAb could be high enough to inactivate the vaccine virus but also too low to protect from field infection, so it is important to find the individual primary vaccination point for each puppy to guarantee the appropriate protection.
Antibody Status Of A Litter
It is possible to determine the antibody status of only one puppy, and use this value as a representative for the other puppies (so-called “fraternal antibody titre”). However, it has to be assumed that all puppies have ingested the same amount of colostrum and developed equally.
By determination of the actual antibody status, an individual decision of the necessity of booster vaccination of the puppy or the adult animal can be made by the veterinarian.
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Why Test?
Why test for Canine Distemper Virus?
Canine Distemper virus (CDV) is one of the most common causes of viral gastroenteritis in dogs worldwide. The disease is recognised by several forms causing gastrointestinal, respiratory, cutaneous and neurologic signs, associated with high mortality rates especially in young and not vaccinated dogs. Antibody titers to CDV are important to prediction of canine health and preparing of a vaccination program.
The Test Sample
- Whole Blood, Plasma or Serum samples may be used with this test
- Whole Blood (without anticoagulants) samples should be used
- If the Serum or Plasma samples cannot be tested immediately, they should be refrigerated at 2 – 8 ◦c for 2 to 3 days. After this period they should be frozen at – 20◦c or below
- Any samples containing precipitate may yield inconsistent test results. Such specimens must be clarified prior to assaying
- The use of haemolytic, lipaemic, icteric or bacterially contaminated samples should be avoided as an erroneous result may occur.
Symptoms
What are the symptoms of Canine Distemper Virus?
The main causes of Canine Distemper Virus are viral gastroenteritis in dogs which in turn causes gastrointestinal, respiratory, cutaneous and neurologic problems.
Clinical signs are
- Sickness
- Diarrhoea
- Dehydration
- Tiredness
Instructions For Use
Instructions For Use
FASTest-CDV-Ab-Instructions-For-Use
